Vesicoureteral Reflux (VUR) often exhibits symptoms linked to urinary tract irritation or infection. In infants, it may present as unexplained fever, poor feeding, irritability, and vomiting. Older children and adults commonly experience recurrent urinary tract infections (UTIs), with symptoms such as fever, abdominal pain, pain or burning during urination, and foul-smelling or cloudy urine.

Frequent urination, a persistent urge to urinate, or bedwetting (enuresis) may also indicate VUR. Some individuals report difficulty fully emptying the bladder, leading to discomfort. In severe cases, VUR can cause back or flank pain due to kidney involvement, and chronic exposure to refluxed urine may result in kidney inflammation or scarring.

If untreated, complications like high blood pressure, proteinuria (protein in urine), or kidney damage can develop. Early recognition of symptoms is critical to managing VUR effectively and preventing long-term urinary and kidney health issues.